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List of ethical pharmaceutical supply information (updated )

Ethical pharmaceutical supply information as of . This information is based on information released by the Ministry of Health, Labor and Welfare. This information may not be all-inclusive. Please check with the manufacturing companies for detailed information. Please note that the supply information does not necessarily correspond to our drug supply situation, and that the supply situation is constantly changing. Even if the supply is restricted, there may be cases where we can supply the product, so please inquiry with us.

*About alternative pharmaceuticals...This information is based on the active ingredients, dosage form, and specifications/units. It does not necessarily mean that the product is currently available.

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Reporting Date/Update Product name Status of supply response of manufacturer Alternative pharmaceuticals Manufacturer Reason Lifting of limited shipments and resolution of supply disruptions expected
DIOVAN OD Tablets 160mg Limited supply available Novartis AG Increased demand Prospects
EXFORGE Combination Tablets Limited supply Novartis AG Increased demand Prospects
EXFORGE Combination OD Tablets Limited supply Novartis AG Increased demand Prospects
Co-DIO Combination Tablets MD Limited supply Novartis AG Increased demand Prospects
Co-DIO Combination Tablets EX Limited supply Novartis AG Increased demand Prospects
Dextromethorphan Hydrobromide Tablets 15mg "TSURUHARA" Limited supply Tsuruhara pharmaceutical Co.,Ltd. Increased demand Undecided
Alprostadil Injection 5μg "NIG" Limited supply available Nichi-Iko Pharmaceutical Co., Ltd. Gifu Plant Increased demand Undecided
Kefral Capsules 250mg Limited supply Kyowa Pharmaceutical Industry Co., Ltd. Other Reasons Undecided
Bezafibrate SR Tablets 200mg "ZE" Limited supply available Zensei Pharmaceutical Industries Company Ltd. Quality problems (including contract manufacturing) Undecided
Pilsicainide Hydrochloride Capsules 25mg "CH" Out of supply available Choseido Pharmaceutical Co., Ltd. Administrative penalties (including contract manufacturing) Undecided
Pilsicainide Hydrochloride Capsules 50mg "CH" Out of supply available Choseido Pharmaceutical Co., Ltd. Administrative penalties (including contract manufacturing) Undecided
Pengood Tablets 250mg Limited supply Nichi-Iko Pharmaceutical Co., Ltd. Increased demand Undecided
Donepezil Hydrochloride OD Tablets 3mg "MOCHIDA" Out of supply available Daito Pharmaceutical Co., Ltd. Deletion of NHI Drug Price
Donepezil Hydrochloride OD Tablets 5mg "MOCHIDA" Out of supply available Daito Pharmaceutical Co., Ltd. Deletion of NHI Drug Price
Donepezil Hydrochloride OD Tablets 10mg "MOCHIDA" Out of supply available Daito Pharmaceutical Co., Ltd. Deletion of NHI Drug Price
Cilostazol OD 50mg "JG" Limited supply available Daito Pharmaceutical Co., Ltd. Increased demand Undecided
Carvedilol Tablets 20mg "NIPRO" Limited supply available NIPRO CORPORATION Increased demand Undecided
Olopatadine Hydrochloride Tablets 5mg "ZE" Limited supply available Zensei Pharmaceutical Industries Company Ltd. Manufacturing problems (including contract manufacturing) Undecided
ILUAMIX Combination Tablets LD "SANWA" Out of supply Daito Pharmaceutical Co., Ltd. Deletion of NHI Drug Price
ILUAMIX Combination Tablets HD "SANWA" Out of supply Daito Pharmaceutical Co., Ltd. Deletion of NHI Drug Price
Isotonic Sodium Chloride Solution Kit "FUSO" Limited supply Fuso Pharmaceutical Industries,Ltd. Increased demand Undecided
LOXOPROFEN Na PAP 100mg "MIKASA" Limited supply mikasa seiyaku co., ltd. Increased demand Undecided
LOXOPROFEN Na PAP 100mg "KYORIN" Limited supply KYORIN Rimedio Co., Ltd. Increased demand Undecided
Sodium Hyaluronate PF Ophthalmic Solution 0.1% "NITTEN" Limited supply Rohto Nitten Co., Ltd. Increased demand Undecided
Sodium Hyaluronate Ophthalmic Solution 0.3% "NITTEN" Limited supply Rohto Nitten Co., Ltd. Increased demand Undecided
Sodium Hyaluronate Ophthalmic Solution 0.1% "Nitten" Limited supply Nippon Beet Sugar Mfg. Co., Ltd. Increased demand Undecided
Sodium Hyaluronate Ophthalmic Solution 0.3% "Nitten" Limited supply Nippon Beet Sugar Mfg. Co., Ltd. Increased demand Undecided
LOXOPROFEN Na Out of supply Sanwa Kagaku Kenkyusho Co., Ltd. Quality problems (including contract manufacturing) No prospects
Nerisona solution 0.1% Out of supply LEO Pharma Deletion of NHI Drug Price
Bismuth Subnitrate "METARU" Out of supply NAKAKITA Co.,Ltd. Quality problems (including contract manufacturing) Undecided
Montelukast Tablets 10mg "TCK" Limited supply Tatsumi Kagaku co.,Ltd. Manufacturing problems (including contract manufacturing) Undecided
Beraprost Sodium Tablets 20μg "VTRS" Limited supply available Viatris(Viatris Healthcare GmbH) Increased demand Undecided
Tosufloxacin Tosilate Tablets 150mg "TCK" Limited supply Tatsumi Kagaku co.,Ltd. Manufacturing problems (including contract manufacturing) Undecided
TOARASET Combination Tablets "TCK" Limited supply Tatsumi Kagaku co.,Ltd. Manufacturing problems (including contract manufacturing) Undecided
Loxoprofen Na PAP 200mg "RAKOOL" Limited supply Toko Pharmaceutical industries Co., Ltd. Increased demand Undecided
TEIKASON Ophthalmic, Otic and Nasal Solution 0.1% Out of supply Teika Pharmaceutical Co., Ltd. Deletion of NHI Drug Price
Benazepril Hydrochloride Tablets 10mg "SAWAI" Out of supply Sawai Pharmaceutical Co., Ltd. Deletion of NHI Drug Price
Paroxetine Tablets 10mg "TAKATA" Out of supply available Takata Seiyaku Co.,Ltd. Other Reasons Undecided
Paroxetine Tablets 20mg "TAKATA" Out of supply available Takata Seiyaku Co.,Ltd. Other Reasons Undecided
Paroxetine Tablets 5mg "TAKATA" Out of supply available Takata Seiyaku Co.,Ltd. Other Reasons Undecided
Zotepine Fine Granules 10% "TAKATA" Limited supply Takata Seiyaku Co.,Ltd. Other Reasons Undecided
MEIACT MS FINE GRANULES 10% FOR PEDIATRIC Limited supply Meiji Seika Pharma Co., Ltd. Increased demand Undecided
Cefditoren Pivoxil Fine Granules 10% for Pediatric "OK" Limited supply OHKURA Pharmaceutical Co., Ltd. Increased demand Undecided
Sarpogrelate Hydrochloride Tablets 50mg "TAKATA" Out of supply available Takata Seiyaku Co.,Ltd. Other Reasons Undecided
Aripiprazole OD Tablets 24mg "TAKATA" Out of supply available Takata Seiyaku Co.,Ltd. Other Reasons Undecided
TAZOPIPE COMBINATION FOR I.V.DRIP INFUSION BAG "DSEP" Limited supply Daiichi Sankyo Espha Co., Ltd. Increased demand Undecided
Soldactone for Intravenous Use 100mg Limited supply Pfizer Japan Inc. Quality problems (including contract manufacturing) Prospects
Soldactone for Intravenous Use 200mg Out of supply Pfizer Japan Inc. Quality problems (including contract manufacturing) Prospects
Hydrophilic Cream "TOHO" Limited supply Toho Yakuhin Co.,Ltd. Increased demand No prospects
LOXOPROFEN Na PAP Limited supply Yoshindo Inc. Increased demand Undecided
Loxoprofen Sodium Pap Limited supply Nichi-Iko Pharmaceutical Co., Ltd. Increased demand Undecided
Alprostadil Injection 10μg "NIG" Limited supply Nichi-Iko Pharmaceutical Co., Ltd. Gifu Plant Increased demand Undecided
LOXOPROFEN SODIUM PAP Out of supply Nipro Pharma Corporation Quality problems (including contract manufacturing) Undecided
Cetirizine Hydrochloride Tablets 5mg "KUNIHIRO" Out of supply available KOKANDO PHARMACEUTICAL CO.,LTD. Deletion of NHI Drug Price
Cetirizine Hydrochloride Tablets 10mg "KUNIHIRO" Out of supply available KOKANDO PHARMACEUTICAL CO.,LTD. Deletion of NHI Drug Price
1% Codeine Phosphate Powder "Hoei" Out of supply Deletion of NHI Drug Price
Codeine Phosphate Tablets 5mg "VTRS" Out of supply Viatris(Viatris Healthcare GmbH) Deletion of NHI Drug Price
1% Dihydrocodeine Phosphate Powder "Hoei" Out of supply Deletion of NHI Drug Price
1% Codeine Phosphate Powder "Hoei" Limited supply available Viatris(Viatris Healthcare GmbH) Increased demand Undecided
1% Dihydrocodeine Phosphate Powder "Hoei" Limited supply available Viatris(Viatris Healthcare GmbH) Increased demand Undecided
Cimetidine Tablets 200mg "KUNIHIRO" Limited supply available KOKANDO PHARMACEUTICAL CO.,LTD. Increased demand No prospects
Cimetidine Tablets 400mg "KUNIHIRO" Limited supply available KOKANDO PHARMACEUTICAL CO.,LTD. Increased demand No prospects
Codeine Phosphate Tablets 5mg "VTRS" Limited supply Viatris(Viatris Healthcare GmbH) Increased demand Undecided
SOLMALT Out of supply Terumo Corporation Other Reasons Undecided
SOLULACT S Out of supply Terumo Corporation Other Reasons Undecided
CEFOTIAM HYDROCHLORIDE FOR INTRAVENOUS Limited supply NIPRO CORPORATION Manufacturing problems (including contract manufacturing) Undecided
LOXOPROFEN SODIUM GEL PATCHES 100mg "TOWA" Out of supply TOWA PHARMACEUTICAL CO., LTD. Quality problems (including contract manufacturing) Undecided
Isoflurane Inhalation Solution "VTRS" Limited supply Viatris(Viatris Healthcare GmbH) Other Reasons Undecided
Funguard 50mg for Infusion Limited supply Sandoz Pharma K.K. Increased demand Undecided
Funguard 75mg for Infusion Limited supply Sandoz Pharma K.K. Increased demand Undecided
Funguard 25mg for Infusion Limited supply Sandoz Pharma K.K. Increased demand Undecided
IRINOTECAN HYDROCHLORIDE I.V. INFUSION Limited supply available NIPRO CORPORATION Increased demand Undecided
IRINOTECAN HYDROCHLORIDE I.V. INFUSION Limited supply available NIPRO CORPORATION Increased demand Undecided
Alprostadil Injection 5μg Syringe "TOWA" Out of supply available TOWA PHARMACEUTICAL CO., LTD. Deletion of NHI Drug Price
Alprostadil Injection 10μg Syringe "TOWA" Out of supply TOWA PHARMACEUTICAL CO., LTD. Deletion of NHI Drug Price
LETROZOLE TABLETS 2.5mg "TOWA" Limited supply TOWA PHARMACEUTICAL CO., LTD. Increased demand Undecided
Levofloxacin Tablets 250mg "NP" Out of supply available Nipro ES Pharma Co., Ltd. Deletion of NHI Drug Price
Levofloxacin Tablets 500mg "NP" Out of supply available Nipro ES Pharma Co., Ltd. Deletion of NHI Drug Price
LEVOFLOXACIN OD TABLETS 500mg "TOWA" Out of supply available TOWA PHARMACEUTICAL CO., LTD. Deletion of NHI Drug Price
Pravastatin Sodium Tablets 5mg "NIPRO" Out of supply available Nipro ES Pharma Co., Ltd. Deletion of NHI Drug Price
Pravastatin Sodium Tablets 10mg "NIPRO" Out of supply available Nipro ES Pharma Co., Ltd. Deletion of NHI Drug Price
Valaciclovir Granules 50% "TOWA" Limited supply TOWA PHARMACEUTICAL CO., LTD. Increased demand Undecided
Tosufloxacin Tosilate Tablets 75mg "NIPRO" Out of supply available Nipro ES Pharma Co., Ltd. Deletion of NHI Drug Price
Tosufloxacin Tosilate Tablets 150mg "NIPRO" Out of supply available Nipro ES Pharma Co., Ltd. Deletion of NHI Drug Price
Dienogest OD Tablets 1mg "TOWA" Limited supply available TOWA PHARMACEUTICAL CO., LTD. Increased demand Undecided
Clopidogrel Tablets 25mg "NP" Out of supply available Nipro ES Pharma Co., Ltd. Manufacturing problems (including contract manufacturing) Undecided
Clopidogrel Tablets 50mg "NP" Out of supply available Nipro ES Pharma Co., Ltd. Manufacturing problems (including contract manufacturing) Undecided
Oxybutynin Hydrochloride Tablets 2mg "TOWA" Out of supply TOWA PHARMACEUTICAL CO., LTD. Deletion of NHI Drug Price
Oxybutynin Hydrochloride Tablets 1mg "TOWA" Out of supply TOWA PHARMACEUTICAL CO., LTD. Deletion of NHI Drug Price
Kallidinogenase Tablets 25 Units "TOWA" Out of supply available TOWA PHARMACEUTICAL CO., LTD. Deletion of NHI Drug Price
Amlodipine Tablets 5mg "SANDOZ" Limited supply available Sandoz K.K. Quality problems (including contract manufacturing) Undecided
Hydrophilic Petrolatum Limited supply Viatris(Viatris Healthcare GmbH) Other Reasons Undecided
Takepron OD Tablets 15 Limited supply available Teva Takeda Yakuhin Ltd. Quality problems (including contract manufacturing) Prospects
Takepron OD Tablets 30 Limited supply Teva Takeda Yakuhin Ltd. Quality problems (including contract manufacturing) Undecided
Landsen Tablets 1mg Limited supply Sumitomo Pharma Co., Ltd. Increased demand Undecided
Landsen Tablets 2mg Limited supply Sumitomo Pharma Co., Ltd. Increased demand Undecided
Rasilez Tablets 150mg Limited supply Novartis AG Other Reasons No prospects
Xylocaine Injection 2% with Epinephrine Limited supply Sandoz Pharma K.K. Manufacturing problems (including contract manufacturing) Undecided
Xylocaine Ophthalmic Solution 4% Limited supply AstraZeneca K.K. Manufacturing problems (including contract manufacturing) Undecided
Fluorometholone Ophthalmic Suspension 0.1% "NITTEN" Out of supply Deletion of NHI Drug Price
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