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List of ethical pharmaceutical supply information (updated )

Ethical pharmaceutical supply information as of . This information is based on information released by the Ministry of Health, Labor and Welfare. This information may not be all-inclusive. Please check with the manufacturing companies for detailed information. Please note that the supply information does not necessarily correspond to our drug supply situation, and that the supply situation is constantly changing. Even if the supply is restricted, there may be cases where we can supply the product, so please inquiry with us.

*About alternative pharmaceuticals...This information is based on the active ingredients, dosage form, and specifications/units. It does not necessarily mean that the product is currently available.

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Reporting Date/Update Product name Status of supply response of manufacturer Alternative pharmaceuticals Manufacturer Reason Lifting of limited shipments and resolution of supply disruptions expected
Sarpogrelate Hydrochloride Tablets 100mg "YD" Out of supply available Yoshindo Inc. Deletion of NHI Drug Price
Ifenprodil Tartrate Tablets 10mg "YD" Out of supply available Yoshindo Inc. Other Reasons Undecided
Ifenprodil Tartrate Tablets 20mg "YD" Out of supply available Yoshindo Inc. Other Reasons Undecided
DENOSINE for I.V. Infusion 500mg Limited supply Mitsubishi Tanabe Pharma Corporation Quality problems (including contract manufacturing) Undecided
Unasyn Fine Granules for Pediatric Use 10% Limited supply Pfizer Japan Inc. Increased demand Undecided
Huscode Combination Syrup Limited supply Viatris(Viatris Healthcare GmbH) Increased demand Undecided
Sawacillin Fine Granules 10% Limited supply LTL Pharma Co., Ltd. Increased demand Undecided
GONATROPIN FOR INJECTION 5000 units Limited supply ASKA Pharmaceutical Co., Ltd. Raw material procurement issues Undecided
Minocycline Hydrochloride for Intravenous Infusion 100mg "Nichiiko" Limited supply Nichi-Iko Pharmaceutical Co., Ltd. Increased demand Undecided
Meropenem Limited supply available Nichi-Iko Pharma Tech Co., Ltd. Increased demand Undecided
Meropenem Limited supply available Nichi-Iko Pharma Tech Co., Ltd. Increased demand Undecided
Cefotiam Limited supply Nichi-Iko Pharma Tech Co., Ltd. Increased demand Undecided
Cefmetazole Limited supply Nichi-Iko Pharma Tech Co., Ltd. Increased demand Undecided
Cefmetazole Limited supply Nichi-Iko Pharma Tech Co., Ltd. Increased demand Undecided
Cefmetazole Limited supply Nichi-Iko Pharma Tech Co., Ltd. Increased demand Undecided
Cefmetazole Limited supply Nichi-Iko Pharma Tech Co., Ltd. Increased demand Undecided
Etanercept BS 10mg Syringe 1.0mL for S.C. Injection "Nichiiko" Out of supply Nichi-Iko Pharmaceutical Co., Ltd. Manufacturing problems (including contract manufacturing) Undecided
ZINC OXIDE OINTMENT Limited supply Nichi-Iko Pharmaceutical Co., Ltd. Increased demand Undecided
Rosuvastatin Tablets 2.5mg "Nichiiko" Out of supply Nichi-Iko Pharmaceutical Co., Ltd. Quality problems (including contract manufacturing) Undecided
Rosuvastatin Tablets 5mg "Nichiiko" Out of supply available Nichi-Iko Pharmaceutical Co., Ltd. Quality problems (including contract manufacturing) Undecided
Loratadine Out of supply available Nichi-Iko Pharmaceutical Co., Ltd. Quality problems (including contract manufacturing) Undecided
Rabeprazole Sodium Tablets 10mg "Nichiiko" Out of supply available Nichi-Iko Pharmaceutical Co., Ltd. Quality problems (including contract manufacturing) Undecided
Rabeprazole Sodium Tablets 20mg "Nichiiko" Out of supply available Nichi-Iko Pharmaceutical Co., Ltd. Quality problems (including contract manufacturing) Undecided
Sodium Risedronate Tablets 2.5mg "Nichiiko" Out of supply Nichi-Iko Pharmaceutical Co., Ltd. Quality problems (including contract manufacturing) Undecided
Mefruside Tablets 25mg "Nichiiko" Out of supply available Nichi-Iko Pharmaceutical Co., Ltd. Quality problems (including contract manufacturing) Undecided
Mesalazine Extended-release Tablets 250mg "Nichiiko P" Limited supply available Nichi-Iko Pharma Tech Co., Ltd. Increased demand Undecided
Mesalazine Extended-release Tablets 500mg "Nichiiko P" Limited supply available Nichi-Iko Pharma Tech Co., Ltd. Increased demand Undecided
Pranlukast Out of supply Nichi-Iko Pharmaceutical Co., Ltd. Manufacturing problems (including contract manufacturing) Undecided
Propranolol Hydrochloride Tablets 10mg "Nichiiko" Out of supply available Nichi-Iko Pharmaceutical Co., Ltd. Quality problems (including contract manufacturing) Undecided
Bromhexine Hydrochloride Tablets 4mg "Nichiiko" Out of supply available Nichi-Iko Pharmaceutical Co., Ltd. Quality problems (including contract manufacturing) Undecided
Saccortin Combination Tablets Out of supply Nichi-Iko Pharmaceutical Co., Ltd. Administrative penalties (including contract manufacturing) Undecided
Voglibose Tablets 0.3mg "Nichiiko" Out of supply Nichi-Iko Pharmaceutical Co., Ltd. Quality problems (including contract manufacturing) Undecided
Fosfomycin Calcium Dry Syrup 40% "Nichiiko" Out of supply Nichi-Iko Pharmaceutical Co., Ltd. Quality problems (including contract manufacturing) Undecided
Famotidine Tablets 10mg "TCK" Out of supply available Tatsumi Kagaku co.,Ltd. Administrative penalties (including contract manufacturing) Undecided
Phenlase Combination Capsules Limited supply Nichi-Iko Pharma Tech Co., Ltd. Increased demand Undecided
Valsartan Tablets 160mg "Nichiiko" Out of supply available Nichi-Iko Pharmaceutical Co., Ltd. Manufacturing problems (including contract manufacturing) Undecided
TERAMURO Combination Tablets AP "Nichiiko" Out of supply Nichi-Iko Pharmaceutical Co., Ltd. Quality problems (including contract manufacturing) Undecided
TERAMURO Combination Tablets BP "Nichiiko" Out of supply Nichi-Iko Pharmaceutical Co., Ltd. Quality problems (including contract manufacturing) Undecided
Tocopherol Nicotinate Capsules 200mg "Nichiiko" Limited supply available Nichi-Iko Pharma Tech Co., Ltd. Manufacturing problems (including contract manufacturing) Undecided
Tranexamic Acid Tablets 250mg "Nichiiko" Limited supply available Nichi-Iko Pharmaceutical Co., Ltd. Raw material procurement issues Undecided
Tizanidine Tablets 1mg "Nichiiko" Limited supply available Nichi-Iko Pharmaceutical Co., Ltd. Increased demand Undecided
UNICON Tablets 200 Out of supply available Nichi-Iko Pharmaceutical Co., Ltd. Quality problems (including contract manufacturing) Undecided
UNICON Tablets 400 Out of supply Nichi-Iko Pharmaceutical Co., Ltd. Quality problems (including contract manufacturing) Undecided
UNICON Tablets 100 Out of supply available Nichi-Iko Pharmaceutical Co., Ltd. Quality problems (including contract manufacturing) Undecided
CETIRIZINE HYDROCHLORIDE Out of supply available Tatsumi Kagaku co.,Ltd. Administrative penalties (including contract manufacturing) Undecided
Cetirizine Hydrochloride Out of supply available Nichi-Iko Pharmaceutical Co., Ltd. Quality problems (including contract manufacturing) Undecided
Cetirizine Hydrochloride Out of supply available Nichi-Iko Pharmaceutical Co., Ltd. Quality problems (including contract manufacturing) Undecided
Cefaclor Fine Granules 10% "Nichiiko" Out of supply Nichi-Iko Pharmaceutical Co., Ltd. Administrative penalties (including contract manufacturing) Undecided
Cefditoren Pivoxil Fine Granules 10% for Pediatric "Nichiiko" Out of supply Nichi-Iko Pharma Tech Co., Ltd. Administrative penalties (including contract manufacturing) Undecided
Zolpidem Tartrate OD Tablets 10mg "Nichiiko" Out of supply Nichi-Iko Pharmaceutical Co., Ltd. Quality problems (including contract manufacturing) Undecided
Spironolactone Tablets 25mg "TCK" Limited supply available Tatsumi Kagaku co.,Ltd. Manufacturing problems (including contract manufacturing) Undecided
Spironolactone Tablets 25mg "Nichiiko" Limited supply available Nichi-Iko Pharmaceutical Co., Ltd. Manufacturing problems (including contract manufacturing) Undecided
Cefaclor Fine Granules 20% "Nichiiko" Limited supply Nichi-Iko Pharmaceutical Co., Ltd. Manufacturing problems (including contract manufacturing) Undecided
Periactin Out of supply Nichi-Iko Pharmaceutical Co., Ltd. Manufacturing problems (including contract manufacturing) Undecided
Clarithromycin Tablets 200mg "TCK" Limited supply available Tatsumi Kagaku co.,Ltd. Manufacturing problems (including contract manufacturing) Undecided
Eperisone Hydrochloride Tablets 50mg "Nichiiko" Limited supply available Nichi-Iko Pharmaceutical Co., Ltd. Manufacturing problems (including contract manufacturing) Undecided
Eletriptan Tablets 20mg "Nichiiko" Out of supply available Nichi-Iko Pharmaceutical Co., Ltd. Quality problems (including contract manufacturing) Undecided
Kallidinogenase Tablets 25 Units "Nichiiko" Out of supply available Nichi-Iko Pharmaceutical Co., Ltd. Quality problems (including contract manufacturing) Undecided
Ambroxol Hydrochloride Tablets 15mg "Nichiiko" Out of supply available Nichi-Iko Pharmaceutical Co., Ltd. Quality problems (including contract manufacturing) Undecided
Imidapril Hydrochloride Tablets 2.5mg "TCK" Out of supply Tatsumi Kagaku co.,Ltd. Manufacturing problems (including contract manufacturing) Undecided
Etizolam Tablets 1mg "TCK" Out of supply Tatsumi Kagaku co.,Ltd. Manufacturing problems (including contract manufacturing) Undecided
Etizolam Tablets 1mg "Nichiiko" Out of supply Nichi-Iko Pharmaceutical Co., Ltd. Quality problems (including contract manufacturing) Undecided
Ambroxol Hydrochloride Tablets 15mg "TCK" Limited supply available Tatsumi Kagaku co.,Ltd. Manufacturing problems (including contract manufacturing) Undecided
Aminovact Limited supply Nichi-Iko Pharmaceutical Co., Ltd. Manufacturing problems (including contract manufacturing) Undecided
Itraconazole Tablets 50mg "Nichiiko" Limited supply available Nichi-Iko Pharmaceutical Co., Ltd. Increased demand Undecided
Carbocisteine Tablets 250mg "TCK" Limited supply Tatsumi Kagaku co.,Ltd. Manufacturing problems (including contract manufacturing) Undecided
Carbocisteine Tablets 500mg "TCK" Limited supply Tatsumi Kagaku co.,Ltd. Manufacturing problems (including contract manufacturing) Undecided
Alacepril Tablets 12.5mg "Nichiiko" Out of supply Nichi-Iko Pharmaceutical Co., Ltd. Quality problems (including contract manufacturing) Undecided
Alacepril Tablets 25mg "Nichiiko" Out of supply available Nichi-Iko Pharmaceutical Co., Ltd. Quality problems (including contract manufacturing) Undecided
Alacepril Tablets 50mg "Nichiiko" Out of supply Nichi-Iko Pharmaceutical Co., Ltd. Quality problems (including contract manufacturing) Undecided
Alendronate Intravenous Infusion Bag 900μg "DK" Limited supply available Daiko Pharmaceutical Co., Ltd. Quality problems (including contract manufacturing) Undecided
Sodium Hyaluronate Ophthalmic Solution 0.1% "KYORIN" Limited supply KYORIN Rimedio Co., Ltd. Increased demand Undecided
Zesulan Fine Granules 0.6% for Pediatric Limited supply Asahi Kasei Pharma Corporation Increased demand Undecided
Bepotastine Besilate Tablets 5mg "DK" Out of supply available Daiko Pharmaceutical Co., Ltd. Other Reasons Undecided
Beraprost Na Tablets 20μg "KYORIN" Out of supply available KYORIN Rimedio Co., Ltd. Quality problems (including contract manufacturing) Undecided
Domperidone Tablets 5mg "KYORIN" Out of supply available KYORIN Rimedio Co., Ltd. Quality problems (including contract manufacturing) Undecided
Tranexamic Acid Capsules 250mg "ASAHI KASEI" Limited supply Asahi Kasei Pharma Corporation Increased demand Undecided
TOARASET Combination Tablets "KYORIN" Limited supply KYORIN Rimedio Co., Ltd. Increased demand Undecided
Amlodipine OD Tablets 2.5mg "KYORIN" Out of supply KYORIN Rimedio Co., Ltd. Quality problems (including contract manufacturing) Undecided
Ciprofloxacin Tablets 100mg "TOWA" Out of supply TOWA PHARMACEUTICAL CO., LTD. Deletion of NHI Drug Price
LOSARHYD Combination Tablets LD "SANDOZ" Out of supply Sandoz K.K. Raw material procurement issues Undecided
LOSARHYD Combination Tablets HD "SANDOZ" Out of supply Sandoz K.K. Raw material procurement issues Undecided
Fluconazole Capsules 50mg "SANDOZ" Out of supply available Sandoz K.K. Administrative penalties (including contract manufacturing) Undecided
Fluconazole Capsules 100mg "SANDOZ" Out of supply available Sandoz K.K. Administrative penalties (including contract manufacturing) Undecided
TOARASET Combination Tablets "SANDOZ" Limited supply Sandoz K.K. Increased demand Undecided
Olcenon Ointment 0.25% Out of supply Sun Pharmaceutical Industries Ltd.(Former Pola Pharma Inc) Raw material procurement issues Undecided
PZC POWDER 1% Out of supply Mitsubishi Tanabe Pharma Corporation Quality problems (including contract manufacturing) Undecided
Biperiden Hydrochloride Tablets 1mg "YOSHITOMI" Out of supply Mitsubishi Tanabe Pharma Corporation Raw material procurement issues Undecided
Loperamide Hydrochloride Capsules 1mg "Horii" Out of supply available Horii Pharmaceutical Ind.,Ltd. Deletion of NHI Drug Price
MaQaid OPHTHALMIC INJECTION 40mg Out of supply WAKAMOTO PHARMACEUTICAL CO., LTD. Quality problems (including contract manufacturing) Undecided
Sodium Hyaluronate Intra-Articular Injection 25mg Syringe "TOWA" Limited supply available TOWA PHARMACEUTICAL CO., LTD. Increased demand Undecided
Nafamostat Mesilate for Injection 50mg "TOWA" Limited supply TOWA PHARMACEUTICAL CO., LTD. Increased demand Undecided
Ethyl Loflazepate Tablets 2mg "TOWA" Out of supply TOWA PHARMACEUTICAL CO., LTD. Administrative penalties (including contract manufacturing) Undecided
Labetalol Hydrochloride Tablets 50mg "TOWA" Limited supply TOWA PHARMACEUTICAL CO., LTD. Increased demand Undecided
Rizatriptan OD Tablets 10mg "TOWA" Limited supply available TOWA PHARMACEUTICAL CO., LTD. Increased demand Undecided
MINOCYCLINE HYDROCHLORIDE TABLETS 100mg "TOWA" Limited supply TOWA PHARMACEUTICAL CO., LTD. Increased demand Undecided
Pramipexole Hydrochloride OD Tablets 0.125mg "TOWA" Limited supply TOWA PHARMACEUTICAL CO., LTD. Increased demand Undecided
Fursultiamine Tablets 25mg "TOWA" Limited supply TOWA PHARMACEUTICAL CO., LTD. Increased demand Undecided
BETASELEMIN COMBINATION TABLETS Limited supply TOWA PHARMACEUTICAL CO., LTD. Increased demand Undecided
BERAPROST SODIUM TABLETS 20μg "TOWA" Limited supply available TOWA PHARMACEUTICAL CO., LTD. Increased demand Undecided
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